Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
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Year : 2012  |  Volume : 33  |  Issue : 2  |  Page : 141-143

A case of a large verrucous swelling over the scrotum

Departmant of Dermatology and STD, Owaisi Hospital and Research Centre, DCMS, Hyderabad, Andhra Pradesh, Departmant of Plastic Surgery, Bangalore Medical College, Bangalore, Karnataka, India

Date of Web Publication9-Oct-2012

Correspondence Address:
Kamal Ahmed
12-2-709/C/191, Padmanabaha Nagar, Hyderabad, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0253-7184.102133

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How to cite this article:
Ahmed K, Singh H, Kumar A S, Ahmed I. A case of a large verrucous swelling over the scrotum. Indian J Sex Transm Dis 2012;33:141-3

How to cite this URL:
Ahmed K, Singh H, Kumar A S, Ahmed I. A case of a large verrucous swelling over the scrotum. Indian J Sex Transm Dis [serial online] 2012 [cited 2023 Dec 1];33:141-3. Available from:

A 45-year-old male patient came to the department of dermatology with complaints of a large exophytic, cauliflower-like verrucous tumor present over the right lateral aspect of the scrotum at the penoscrotal junction [Figure 1]. The tumor had evolved progressively for 3 to 4 years to the present size i.e 5 × 6 cm in size.
Figure 1: Large exophytic, cauliflower like verrucous tumor present over the penoscrotal junction

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Routine investigations like complete blood picture, liver function test (LFT), and renal function test (RFT) were within normal limits. HIV1 and 2 testing was negative. An extensive surgical excision was performed and the excised tissue was sent for histopathological examination. It revealed orthokeratosis, parakeratosis, with acanthosis and marked papillomatosis. The cells displayed a vacuolated cytoplasm with irregular and large nuclei scattered in the stratum malpighi (koilocytes)

[Figure 2].There were no sighs of dysplasia in the epidermis dermis showing polymorphous infiltrate.
Figure 2: HPE revealed orthokeratosis, parakeratosis with acanthosis and marked papillomatosis (H and E, 40 X)

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   References Top

1.Gholam P, Enk A, Hartschuh W. Successful surgical management of giant condyloma acuminatum (Buschke-Löwenstein tumor) in the genitoanal region: A case report and evaluation of current therapies. Dermatology 2009;218:56-9.  Back to cited text no. 1
2.Bertram P, Treutner KH, Rübben A, Hauptmann S, Schumpelick V. Invasive squamous-cell carcinoma in giant anorectal condyloma (Buschke-Löwenstein tumor). Langenbecks Arch Chir 1995;380:115-8.  Back to cited text no. 2
3.Meli BG, Ramos H, Gomez LA. Giant condyloma acuminatum (Buschke-Loewenstein tumour) of the scrotum. Eur J Plast Surg 1994;17:43-7.  Back to cited text no. 3
4.Sepou A, Zoguereh DD. Giant anovulvar condyloma acuminata revealing HIV-1 seropositivity in a Centrafrican patient. Med Trop 1998;58:378-80.  Back to cited text no. 4
5.Granados E, Palou J, Rios G, Vicente J. Urologic pathology in patients positive for anti-HIV antibodies. Actas Urol Esp 1989;13:378-80.  Back to cited text no. 5
6.Garazzino S, Canavese F, Coppo P, Cortese MG, Pucci A, Mignone F, et al. An infant presenting with a voluminous exophytic perineal mass. Pediatr Infect Dis J 2010;29:577-83.  Back to cited text no. 6
7.el Mejjad A, Dakir M, Tahiri M, Attar H, Cherkaoui A, Araki A, et al. [Giant condyloma acuminata -- Buschke Lowenstein tumor (report of 3 cases)]. Prog Urol 2003;13:513-7.  Back to cited text no. 7
8.Qarro A, Ait Ali A, Choho A, Alkandry S, Borki K. [Anorectal Buschke-Lowenstein tumor. (Three cases report)]. Ann Chir 2005;130:96-100.  Back to cited text no. 8
9.Gillard P, Vanhooteghem O, Richert B, De La Brasine M. Tumor de Buschke-Loewenstein. Ann Dermatol Venereol 2005;132:98-9.  Back to cited text no. 9
10.Buschke A, Löwenstein L. Über carcinomähnliche condylomata accuminata des Penis. Klin Wochenschr 1925;4:1726-8.  Back to cited text no. 10
11.Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J. Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour. Surgeon 2006;4:378-83.  Back to cited text no. 11
12.Wiltz OH, Torregrosa M, Wiltz O. Autogenous vaccine: The best therapy for perianal condyloma acuminata? Dis Colon Rectum 1995;38:838-41.  Back to cited text no. 12


  [Figure 1], [Figure 2], [Figure 3]


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