| ORIGINAL ARTICLE |
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| Year : 2012 | Volume
: 33
| Issue : 2 | Page : 98-101 |
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Audio-vestibular function in human immunodeficiency virus infected patients in India
Suma Susan Mathews, Rita Ruby Albert, Anand Job
Department of ENT, Christian Medical College, Vellore, India
Correspondence Address:
Suma Susan Mathews
Department of ENT, Christian Medical College, Vellore 632 004
India
 Source of Support: The study was supported in part by the FLUID research funds, Christian Medical College, Vellore., Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7184.102115
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Objective: As the acquired immunodeficiency syndrome (AIDS) epidemic shows no signs of abating, the impact of AIDS is felt more in the developing countries due to socioeconomic reasons. The possibility of drug-induced ototoxicity also adds to the risk of audio vestibular dysfunction. We sought to determine if there was a difference between the audio-vestibular function in the asymptomatic human immunodeficiency virus (HIV) infected patients and patients with AIDS. Study Design: A prospective, cross-sectional study Setting: A tertiary care center in South India Materials and Methods: The audio-vestibular system of 30 asymptomatic HIV positive subjects (group 1) and 30 subjects with AIDS (group 2), and age-matched 30 healthy controls (group 3) were assessed using pure tone audiometry and cold caloric test. Results: Sixteen patients each, in group 1 and group 2 and four subjects in the control group were detected to have a hearing loss indicating significantly more HIV infected individuals (group 1 and 2) were having hearing loss (P=0.001). Kobrak's (modified) test showed 27% of patients in group 1 and 33% of patients in group 2 and none in the group 3 had a hypofunctioning labyrinth (P=0.001). Conclusion: It seems that the human immunodeficiency virus does affect the audio-vestibular pathway. There was a significant incidence of audio-vestibular dysfunction among the HIV infected patients, as compared to the control population (P=0.001) and no significant difference between the asymptomatic HIV seropositive patients and AIDS patients. Majority of the patients had no otological symptoms. |
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