Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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Year : 2022  |  Volume : 43  |  Issue : 1  |  Page : 82-84

Intracranial lymphoma in human immunodeficiency virus-infected patients: A diagnostic dilemma?

1 Center for Excellence in HIV/AIDS, Ashirwad Hospital, Thane, Maharashtra, India
2 Department of Radiotherapy, M. S. Ramaiah Medical College, Bengaluru, Karnataka, India

Correspondence Address:
Dr. Rajkumar Gurubuxrai Harjani
Center of Excellence for HIV/AIDS, Ashirwad Hospital, Thane East, Thane - 400 603, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijstd.ijstd_10_21

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Primary central nervous system (CNS) lymphoma is an aggressive malignancy which constitutes one of the acquired immunodeficiency syndrome -defining illnesses. Early diagnosis and timely management can increase the chances of cure. Although many times the diagnosis is straightforward, we present a case of primary CNS lymphoma in a human immunodeficiency virus--positive individual which posed as a major diagnostic dilemma with initially normal imaging findings. A 42-year-old male presented with unremitting fever and a perianal ulcer for 3 months. A battery of diagnostic tests were negative, including a positron emission tomography-computed tomography scan and a magnetic resonance imaging brain. With unresolving symptoms and a high index of suspicion as he developed dizziness and loss of balance, the same were repeated which confirmed a space-occupying lesion in the cerebellum. Although treatment was instituted, the patient did not recover and died in the 4th month of treatment.

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