Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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Year : 2022  |  Volume : 43  |  Issue : 2  |  Page : 201-202

Jarisch–Herxheimer reaction in syphilis

1 Androgynaecare, Department of Gynaecology and Sexual Medicine, Cochin, Kerala, India
2 Department of Dermatology and Sexual Medicine, Shifa Hospitals, Tirunelveli, Tamil Nadu, India

Correspondence Address:
Dr. S Murugan
Consultant in Sexual Medicine and HIV Medicine, Shifa Hospitals, 82, Kailasapuram, Tirunelveli, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijstd.ijstd_3_22

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Jarisch–Herxheimer reaction (JHR) is a focal, local, or systemic reaction, which follows the first dose of antisyphilitic remedy. JHR is a self-limiting reaction. The appearance of secondary syphilitic rashes following injection of benzathine penicillin was not so common nowadays to meet with JHR. Rashes were resolved completely a week after the injection. This case was reported to alert the physicians about the appearance of secondary syphilitic rashes following the antisyphilitic treatment which could be confused with hypersensitive reactions of penicillin.

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