| CASE REPORT |
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| Year : 2023 | Volume
: 44
| Issue : 1 | Page : 79-81 |
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Jarisch‒Herxheimer reaction
Manjyot Gautam, Sahil Sethi, Nitin J Nadkarni
Department of Dermatology, Venerology and Leprosy, Dr. D.Y. Patil Medical College and Hospital, Navi Mumbai, Maharashtra, India
Correspondence Address:
Dr. Sahil Sethi
Department of Dermatology, Venerology and Leprosy, Dr. D.Y. Patil Medical College and Hospital, Navi Mumbai, Maharashtra
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijstd.ijstd_107_22
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Syphilis is caused by a spirochete, Treponema pallidum. Diagnosis of syphilis is made with a venereal disease research laboratory test. Treatment of choice is intramuscular injection benzathine Penicillin. The Jarisch‒Herxheimer reaction (JHR) is a transient immunological phenomenon that can occur in patients during treatment for syphilis with penicillin. It is a rare phenomenon but can be a potentially severe one. It manifests clinically with short-term constitutional symptoms such as fever, chills, headache, and myalgia, besides exacerbation of existing cutaneous lesions. We report the case of a 24-year-old man presenting with JHR posttreatment with benzathine penicillin.
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